Edit |   |
---|---|
Antigenic Specificity | SR-2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SR-2A Polyclonal Antibody detects endogenous levels of SR-2A protein. HTR2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in HTR2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human SR-2A at AA rangle: 400-480 |
Other Names | [Rabbit SR-2A; HTR2A; HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; Serotonin receptor 2A] |
Gene, Accession # | [SR-2A], Gene ID: 3356, NCBI: NP_000612.1, UniProt: P28223 |
Catalog # | MBS9705439 |
Price | $130, $220, $325 |
Order / More Info | SR-2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |