Human/Mouse/Rat CD47 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman/Mouse/Rat CD47
Clone[MIAP410]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatunconjugated
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionCD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPalpha, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
Immunogenn/a
Other Names[Human/Mouse/Rat CD47; Leukocyte surface antigen CD47; Cd47; Integrin-associated protein; IAP]
Gene, Accession #[CD47], Gene ID: 961, NCBI: NP_001768.1, UniProt: Q08722
Catalog #MBS2553777
Price$110, $140
Order / More InfoHuman/Mouse/Rat CD47 Antibody from MYBIOSOURCE INC.
Product Specific References1. Gresham HD, Dale BM, Potter JW, et al. J Exp Med. 2000; 191(3):515-528. 2. Jiang P, Lagenaur CF, Narayanan V. J Biol Chem. 1999; 274(2):559-562. 3. Lindberg FP, Bullard DC, Caver TE, Gresham HD, Beaudet AL, Brown EJ. Science. 1996; 274(5288):795-798. 4. Lindberg FP, Gresham HD, Schwarz E, Brown EJ. J Cell Biol. 1993; 123(2):485-496. 5. Mi ZP, Jiang P, Weng WL, Lindberg FP, Narayanan V, Lagenaur CF. J Comp Neurol. 2000; 416(3):335-344. 6. Oldenborg PA, Zheleznyak A, Fang YF, Lagenaur CF, Gresham HD, Lindberg FP. Science. 2000; 288(5473):2051-2054. 7. Reinhold MI, Lindberg FP, Plas D, Reynolds S, Peters MG, Brown EJ. J Cell Sci. 1995 November; 108(Pt 11):3419-3425.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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