Human CD49d Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD49d
Clone[BU49]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.025 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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DescriptionCD49d is a 150 kD alpha integrin chain known as alpha4 integrin or VLA-4 alpha chain. It forms a heterodimer with either integrin beta1 (alpha4beta1, VLA-4) or beta7 (alpha4beta7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. alpha4beta7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activ
Immunogenn/a
Other Names[Human CD49d; Integrin alpha-4; ITGA4; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; CD49d]
Gene, Accession #[CD49d], Gene ID: 3676, NCBI: NP_000876.3, UniProt: P13612
Catalog #MBS2553813
Price$75, $135
Order / More InfoHuman CD49d Antibody from MYBIOSOURCE INC.
Product Specific References1. Elices M, Ed.1995. Springer Semin. Immunopathol. 16(4). 2. Lobb RR and Helmer ME. et al. 1994. J. Clin. Invest. 94:1722.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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