TAB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTAB1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody detects endogenous levels TAB1(N-terminus) and does not cross-react with related proteins. UniPort Summary Function: May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis. Entrez Summary: The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative
ImmunogenImmunogen: Purified recombinant human TAB1(N-terminus) protein fragments expressed in E Coli.
Other Names[3?-Tab1; MAP3K7IP1], [TAB1; TAB1; 3'-Tab1; MAP3K7IP1; MAP3K7IP1; TAK1-binding protein 1]
Gene, Accession #[TAB1], Gene ID: 10454, NCBI: NP_006107.1, UniProt: Q15750
Catalog #MBS857839
Price$300
Order / More InfoTAB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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