REN Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-REN antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | REN |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Renin is a secreted proteinase whose enzymatic activity is to convert angiotensinogen into angiotensin I in the plasma, initiating a process that results in an elevation of blood pressure and increased sodium retention by the kidney (1). Renin is synthezed in kidney as a procursor, prorenin, which is released into circulation. Both renin and prorenin can bind to (pro)renin receptor and induce angiotensin-independent signaling events leading to activation of MAPKs and up-regulation of TGF-beta1 and matrix proteins (2, 3). Defects in renin can cause renal tubular dysgenesis, a severe autosomal recessive disorder of renal tubular development (4, 5). |
| Immunogen | Immunogen: Recombinant protein of human REN Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [FLJ10761] |
| Gene, Accession # | [REN], Gene ID: 5972, NCBI: NP_000528.1, UniProt: P00797 |
| Catalog # | MBS8501687 |
| Price | $310 |
| Order / More Info | REN Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Castrop, H. et al. (2010) Physiol Rev 90, 607-73. 2. Ichihara, A. et al. J Nephrol 22, 306-11. 3. Nguyen, G. (2010) Ann Med 42, 13-8. 4. Lacoste, M. et al. (2006) J Am Soc Nephrol 17, 2253-63. 5. Gubler, M.C. and Antignac, C. (2010) Kidney Int 77, 400-6. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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