Human Junctional adhesion molecule C (JAM-C) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Junctional adhesion molecule C (JAM-C)
Clone[4M35]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Neutr
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DescriptionMembers of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1.
ImmunogenAntibody Generation: Monoclonal antibodies were produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with recombinant human JAM-C. This IgG1 antibody was purified from supernatant on a Protein G chromatography column.
Other Names[JAM3; JAMC; JAM-C], [JAM3; JAM3; JAMC; JAM-2; JAM-3; JAM-C; JAM-C; JAM-3]
Gene, Accession #[JAM-C], Gene ID: 83700, NCBI: NP_001192258.1, UniProt: Q9BX67
Catalog #MBS690010
Price$490
Order / More InfoHuman Junctional adhesion molecule C (JAM-C) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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