SOX10 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SOX10 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat. predicted: porcine (100%), chicken (89%), goat (100%) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SOX10 Antibody is predicted to not cross-react with other SOX familiy members. SOX10 Antibody: SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and the determination of the cell fate (1). The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins (2). This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development (2). Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschprung disease (3). SLC30A8 expression in beta-cells was found to be influenced by cytokine expression, particularly IFN-gamma a |
| Immunogen | Immunogen: SOX10 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human SOX10. Buffer: SOX10 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [SOX10; SRY (sex determining region Y)-box 10; DOM;WS4; PCWH; WS2E; WS4C; SRY-box 10], [SOX10; SOX10; DOM; WS4; PCWH; WS2E; WS4C] |
| Gene, Accession # | [SOX10], Gene ID: 6663, NCBI: NP_008872, UniProt: P56693 |
| Catalog # | MBS154448 |
| Price | $375 |
| Order / More Info | SOX10 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Pusch C, Hustert E, Pfeifer D, et al. The SOX10/Sox10 gene from human and mouse: sequence, expression, and transactivation by the encoded HMG domain transcription factor. Hum. Genet. 1998; 103:115-23. 2. Rehberg S, Lischka P, Glaser G, et al. Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation. Mol. Cell Biol. 2002; 22:5826-34. 3. Pingault V, Bondurand N, Kuhlbrodt K, et al. SOX10 mutations in patients with Waardenburg-Hirschprung disease. Nat. Genet. 1998; 18:171-3. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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