Human TLR2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human TLR2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human TLR2 |
| Clone | [2B4A1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human Toll-like Receptor 2 (TLR2). The Toll-like receptor (TLR) family is comprised of Type I transmembrane proteins characterized by an extracellular leucine-rich domain and a cytoplasmic tail that contains a conserved region call the Toll/IL-1 (TIR) domain. First discovered in Drosophila, TLRs recognize specific molecular patterns that are present in microbial components and respond to these components in order eliminate or limit invading microbes. To date, ten mammalian homologs of TLRs have been described. Activation of TLR2 leads to the initiation of apoptosis and the activation of the NK- kappa B pathway by the adaptor molecule MyD88. TLR2 recognizes and is activated by components from a broad variety of microorganisms in |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS670136 |
| Price | $285 |
| Order / More Info | Human TLR2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Takeuchi, O., T. Kawai, P.F. Muhlradt, M. Morr, J.D. Radolf, A. Zychlinsky, K. Takeda, and S. Akira. 2001. Int. Immunol. 13:933.2. Schwandner, R., R. Dziarski, H. Wesche, M. Rothe, and C.J. Kirschning. 1999. J. Biol. Chem. 274:17406.3. Campos, M.A., I.C. Almeida, O. Takeuchi, S. Akira, E.P. Valente, D.O. Procopio, L.R. Travassos, J.A. Smith, D.T. Golenbock, and R.T. Gazzinelli. 2001. J. Immunol. 167:416.4. Aliprantis, A.O., R. Yang, D.S. Weiss, P. Godowski, and A. Zychlinsky. 2000. EMBO J. 19:3325.5. Wyllie, D.H., E. Kiss-Toth, A. Visintin, S.C. Smith, S. Boussouf, D.M. Segal, G.W. Duff, and S.K. Dower. 2000. J. Immunol. 165:7125.6. Hirschfeld, M., C.J. Kirschning, R. Schwandner, H. Wesche, J.H. Weis, R.M. Wooten, and J.J. Weis. 1999. J. Immunol. 163:2382.7. Lien, E., T.J. Sellati, A. Yoshimura, T.H. Flo, G. Rawadi, R.W. Finberg, J.D. Carroll, T. Espevik, R.R. Ingalls, J.D. Radolf, and D.T. Golenbock. 1999. J. Biol. Chem. 274:33419.8. Aliprantis, A.O., R. Yang, M. R. Mark, S. Suggett, B. Devaux, J.D. Radolf, G.R. Klimpel, P. Godowski, and A. Zychlinsky. 1999. Science 285:736.9. Yoshimura, A., E. Lien, R.R. Ingalls, E. Tuomanen, R. Dziarski, and D. Golenbock. 1999. J. Immunol. 163:1.10. Opitz, B., N.W. Schroder, I. Spreitzer, K.S. Michelsen, C. J. Kirschning, W. Hallatschek, U. Zahringer, T. Hartung, U.B. Gobel, and R.R. Schumann. 2001. J. Biol. Chem. 276:22041.11. Hajjar, A.M., D.S. O'Mahony, A. Ozinsky, D.M. Underhill, A. Aderem, S.J. Klebanoff, and C.B. Wilson. 2001. J. Immunol. 166:15.12. Massari, P., P. Henneke, Y. Ho, E. Latz, D.T. Golenbock, and L.M. Wetzler. 2002. J. Immunol. 168:1533.13. Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Immunity 11:443.14. Means, T.K., S. Wang, E. Lien, A. Yoshimura, D.T. Golenbock, and M.J. Fenton. 1999. J. Immunol. 163:3920.15. Underhill, D.M., A. Ozinsky, A.M. Hajjar, A. Stevens, C.B. Wilson, M. Bassetti, and A. Aderem. 1999. Nature 401:811.16. Alexopoulou, L., V. Thomas, M. Schnare, Y. Lobet, J. Anguita, R.T. Schoen, R. Medzhitov, E. Fikrig, and R. A. Flavell. 2002. Nat. Med. 8:878. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies