PAK1 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PAK1 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: bovine, rat, mouse, Xenopus) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PAK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 241-275 amino acids from the Central region of human PAK1. Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase pathway. Phosphorylates and activates MAP2K1, and thereby mediates activation of downstream MAP k |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK; PAK1] |
| Gene, Accession # | [PAK1], Gene ID: 5058, NCBI: NP_001122092.1, UniProt: Q13153 |
| Catalog # | MBS9214926 |
| Price | $165, $370 |
| Order / More Info | PAK1 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Brown J.L.,et al.Curr. Biol. 6:598-605(1996). Sells M.A.,et al.Curr. Biol. 7:202-210(1997). Reid T.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases. Taylor T.D.,et al.Nature 440:497-500(2006). Manser E.,et al.Mol. Cell. Biol. 17:1129-1143(1997). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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