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Antigenic Specificity | ITPR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1850-1950 of human ITPR1 (XP 011531985.1). |
Other Names | [ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94] |
Gene, Accession # | [ITPR1], Gene ID: 3708, NCBI: NP_001093422.2, UniProt: Q14643 |
Catalog # | MBS8547119 |
Price | $280 |
Order / More Info | ITPR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |