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Antigenic Specificity | ABL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The c-Abl proto-oncogene encodes a nonreceptor protein tyrosine kinase that is ubiquitously expressed and highly conserved in metazoan evolution. c-Abl protein is distributed in both the nucleus and the cytoplasm of cells. It is implicated in regulating cell proliferation, differentiation, apoptosis, cell adhesion and stress responses (1-3). c-Abl kinase activity is increased in vivo by diverse physiological stimuli including integrin activation, PDGF stimulation and binding to c-Jun, Nck and RFX1 (2,4). The in vivo mechanism of regulation of c-Abl kinase activity is not completely understood. Tyr245 is located in the linker region between the SH2 and catalytic domains. This positioning is conserved among Abl family members. Phosphorylation |
Immunogen | Immunogen: C term -peptide of human ABL1 Calculated Molecular Weight: 123kDa |
Other Names | [c-Abl: ABL1; ABL; JTK7; bcr/abl; c-ABL; p150; v-abl], [ABL1; ABL1; ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl; ABL; JTK7] |
Gene, Accession # | [ABL1], Gene ID: 25, NCBI: P00519.4, UniProt: P00519 |
Catalog # | MBS125449 |
Price | $200, $275, $430 |
Order / More Info | ABL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |