IL-1beta Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | IL-1beta |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, zebrafish |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The protein encoded by the gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytcokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to the inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
| Immunogen | Immunogen: Recombinant Protein of human IL1B |
| Other Names | [IL1B; IL-1beta; IL-1b; Interleukin-1 beta; IL-1 beta; Catabolin; IL1F2; IL1B], [IL1B; IL1B; IL-1; IL1F2; IL1-BETA; IL1F2; IL-1 beta] |
| Gene, Accession # | Gene ID: 3553, NCBI: NP_000567.1, UniProt: P01584 |
| Catalog # | MBS125139 |
| Price | $235, $350 |
| Order / More Info | IL-1beta Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Dinarello, C.A. (1998) Int. Rev. Immunol. 16, 457-499. 2. Burns, K. et al. (1998) J. Biol. Chem. 273, 12203-12209. 3. Cao, Z. et al. (1996) Nature 383, 443-446. 4. Cao, Z. et al. (1996) Science 271, 1128-1131. 5. Wesche, H. et al. (1997) Immunity 7, 837-847. 6. NinomiyaTsuji, J. et al. (1999) Nature 398, 252-256. 7. Thornberry, N. A. et al. (1992) Nature 356, 768-774. 8. Cerretti, D. P. et al. (1992) Science 256, 97-100. 9. Grahames, C.B. et al. (1999) Br J Pharmacol 127, 1915-21. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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