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Antigenic Specificity | CH25H (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CH25H antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 47-76 amino acids from human CH25H. Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation. |
Immunogen | n/a |
Other Names | [Cholesterol 25-hydroxylase; 1.14.99.38; Cholesterol 25-monooxygenase; h25OH; CH25H] |
Gene, Accession # | [CH25H], Gene ID: 9023, NCBI: NP_003947.1, UniProt: O95992 |
Catalog # | MBS9231078 |
Price | $165, $370 |
Order / More Info | CH25H (N-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Lund E.G.,et al.J. Biol. Chem. 273:34316-34327 (1998). Ota T.,et al.Nat. Genet. 36:40-45 (2004). Deloukas P.,et al.Nature 429:375-381 (2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Riemenschneider M.,et al.Neurobiol. Aging 25:1305-1308 (2004). |