RIG-I (Center), 585-614 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | RIG-I (Center), 585-614 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RIG-I antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 585-614 amino acids from the Central region of human RIG-I. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. RIG-I contains RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, RIG-I triggers a transduction cascade involving MAVS/IPS1, which results in the a |
| Immunogen | n/a |
| Other Names | [Probable ATP-dependent RNA helicase DDX58; DEAD box protein 58; RIG-I-like receptor 1; RLR-1; Retinoic acid-inducible gene 1 protein; RIG-1; Retinoic acid-inducible gene I protein; RIG-I; DDX58] |
| Gene, Accession # | [DDX58], Gene ID: 23586, NCBI: NP_055129.2, UniProt: O95786 |
| Catalog # | MBS9210898 |
| Price | $165, $370 |
| Order / More Info | RIG-I (Center), 585-614 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Li, K., et al., J. Biol. Chem. 280(17):16739-16747 (2005). Breiman, A., et al., J. Virol. 79(7):3969-3978 (2005). Cui, X.F., et al., Biochem. Cell Biol. 82(3):401-405 (2004). Imaizumi, T., et al., Life Sci. 75(10):1171-1180 (2004). Imaizumi, T., et al., Endothelium 11 (3-4), 169-173 (2004) (): (). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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