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Antigenic Specificity | EWSR1 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EWSR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 328-362 amino acids from the Central region of human EWSR1. Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
Immunogen | n/a |
Other Names | [RNA-binding protein EWS; EWS oncogene; Ewing sarcoma breakpoint region 1 protein; EWSR1; EWS] |
Gene, Accession # | [EWSR1], Gene ID: 2130, NCBI: NP_001156757.1, UniProt: Q01844 |
Catalog # | MBS9209010 |
Price | $165, $370 |
Order / More Info | EWSR1 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Delattre O.,et al.Nature 359:162-165(1992). Plougastel B.,et al.Genomics 18:609-615(1993). Zucman-Rossi J.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases. Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004). Ota T.,et al.Nat. Genet. 36:40-45(2004). |