TNK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNK1
Clone[1B5G3; 3F11H6]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
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DescriptionTNK1: tyrosine kinase, non-receptor, 1. TNK1 is a nonreceptor tyrosine kinase(NRPTK). These kinases, like members of the SRC (MIM 190090) and JAK (see MIM 147795) families, mediate intracellular signaling downstream of receptor activation.Tnk1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.
ImmunogenImmunogen: Purified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli.
Other Names[MGC46193; TNK1]
Gene, Accession #[TNK1], Gene ID: 8711, NCBI: AAH35782.1, UniProt: Q13470
Catalog #MBS8538430
Price$280
Order / More InfoTNK1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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