Mono-Methyl-P53 (Lys370) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMono-Methyl-P53 (Lys370)
Clone[4A1]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG
FormatProtein A purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration1mg/mL
ApplicationsImmunohistochemistry (IHC) Paraffin (IHC-p)
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DescriptionThe protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
ImmunogenImmunogen: Synthetic Peptide Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.4 Conjugation: Unconjugated
Other Names[cellular tumor antigen p53 isoform a; Cellular tumor antigen p53; cellular tumor antigen p53; tumor protein p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53]
Gene, Accession #[P53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637
Catalog #MBS2549849
Price$110, $150, $225
Order / More InfoMono-Methyl-P53 (Lys370) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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