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Antigenic Specificity | CYP1A1 (C-term), 377-405 |
Clone | [655CT6.1.2] |
Host Species | Mouse |
Reactive Species | human (predicted reactivity: monkey) |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.37 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CYP1A1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1. This gene, CYP1A1, encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and itsexpression is induced by some polycyclic aromatic hydrocarbons(PAHs), some of which are found in cigarette smoke. The enzyme'sendogenous substrate is unknown; however, it is able to metabolizesome PAHs to carcinogenic intermediates. The gene has been< |
Immunogen | n/a |
Other Names | [Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1; CYP1A1] |
Gene, Accession # | [CYP1A1], Gene ID: 1543, NCBI: NP_000490.1, UniProt: P04798 |
Catalog # | MBS9200271 |
Price | $165, $370 |
Order / More Info | CYP1A1 (C-term), 377-405 Antibody from MYBIOSOURCE INC. |
Product Specific References | Pande, M., et al. Mol. Carcinog. 49(11):974-980(2010) Sabitha, K., et al. Cancer Epidemiol 34(5):587-592(2010) Kumar, V., et al. Chemosphere 81(4):464-468(2010) Yamaguti, G.G., et al. Acta Haematol. 124(3):182-184(2010) Olsen, J.V., et al. Cell 127(3):635-648(2006) |