p63, alpha (KET, p51, p40, AIS, p73L) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | p63, alpha (KET, p51, p40, AIS, p73L) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes endogenous levels of total human p63, alpha at ~75kD. Detects both full length TAp63, alpha and truncated delta, Np63, alpha, but not p63, beta or p63, gamma. The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis (1). In addition to p53, mammalian cells contain two p53 family members, p63 and p73, which are similar to p53 in both structure and function (2). While p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors (2). Amplification of the p63 gene is frequently observed in squamous cell carcinomas of the lung, head and neck (2,3). The p63 gene c |
| Immunogen | Immunogen: Synthetic peptide corresponding to residues within the C-terminus of human p63, alpha (KLH). Species Sequence Homology: Chicken. |
| Other Names | n/a |
| Gene, Accession # | NCBI: AFD05170.1 |
| Catalog # | MBS625598 |
| Price | $550 |
| Order / More Info | p63, alpha (KET, p51, p40, AIS, p73L) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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