CD274 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CD274 |
| Clone | [9E32] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | 0.5 mg |
| Concentration | 1mg/ml |
| Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Functional Assays. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes mouse CD274. CD274, also known as B7-H1 and PD-1L, a cell surface glycoprotein which is a member of the B7 family of co-stimulatory molecules. CD274 is expressed constitutively on macrophages and dendritic cells, and is induced on activated T-cells, B-cells, endothelial cells and epithelial cells in response to Interferons alpha, beta and gamma. CD274 is reported to possess dual functions; inhibition of activated effector T cells and co-stimulation of naïve T cells. CD274 inhibits proliferation of activated T cells via ligation to the co-inhibitory molecule CD279 (programmed death-1; PD-1) leading to the secretion of the regulatory cytokine interleukin-10. CD274 has also been shown to costimulate early T cell priming and dif |
| Immunogen | Immunogen: Mouse CD274-transfected L5178Y cells |
| Other Names | [-CD274, Low Endotoxin (B7-h1 Protein, B7-H1, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1)], [CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296] |
| Gene, Accession # | Gene ID: 29126, UniProt: Q0GN75 |
| Catalog # | MBS607584 |
| Price | $870 |
| Order / More Info | CD274 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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