SETDB2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SETDB2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SETDB2 antibody detects endogenous levels of total SETDB2. Description: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.Similarity: In the pre-SET domain, Cys residues bind 3 zinc ions that are arranged in a triangular cluster; some of these Cys residues contribute to the binding of two zinc ions wit |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Chromosome. Tissue Specificity: Ubiquitous. Highest expression in heart, testis and ovary. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Zebrafish (100%), Bovine (90%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [C13orf4; Chromosome 13 open reading frame 4; Chronic lymphocytic leukemia deletion region 8; Chronic lymphocytic leukemia deletion region gene 8; Chronic lymphocytic leukemia deletion region gene 8 protein; Clld8; CLLL8; Gm293; H3-K9-HMTase; Histone H3-K9 methyltransferase; Histone-lysine N-methyltransferase SETDB2; KMT1F; Lysine N-methyltransferase 1F; Probable histone-lysine N-methyltransferase H3 lysine-9 specific; SEB2; SET domain bifurcated 2; SET domain protein, bifurcated, 2; SETB2_HUMAN; Setdb2] |
| Gene, Accession # | [SETDB2], Gene ID: 83852, NCBI: NP_001153780.1, UniProt: Q96T68 |
| Catalog # | MBS9604080 |
| Price | $240, $280 |
| Order / More Info | SETDB2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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