Edit |   |
---|---|
Antigenic Specificity | Human GFAP |
Clone | [SB61a1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human GFAP. Glial Fibrillary Acid Protein (GFAP) was discovered by Bignami et al 2 as a major fibrous protein of multiple sclerosis plaques. It was subsequently found to be a member of the 10 nm or intermediate filament protein family, specifically the intermediate filament protein family Class III, which also includes peripherin, desmin and vimentin. GFAP is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves.3 Many types of brain tumors, presumably of astrocytic origin, heavily express GFAP. In addition, neural stem cells frequently strongly express GFAP. It is also foun |
Immunogen | Immunogen: Recombinant human Glial Fibrillary Acid Protein (GFAP) |
Other Names | [Glial fibrillary acidic protein, intermediate filament protein.], [GFAP; GFAP; FLJ45472; GFAP] |
Gene, Accession # | Gene ID: 2670, UniProt: P14136 |
Catalog # | MBS670159 |
Price | $255 |
Order / More Info | Human GFAP Antibody from MYBIOSOURCE INC. |
Product Specific References | 1) Lukas, Z. et al. 1989. Expression of vimentin and glial fibrillary acid protein in human developing spinal cord. Histochem. J. 21:693.3) Brenner, M. et al. 2001. Mutations in GFAP, encoding glial fibrillary acid protein, are associated with Alexander's Disease. Nat. Genet. 7:118-120. |