Acetylated Lysine Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAcetylated Lysine
Clone[7F8]
Host SpeciesMouse
Reactive Speciesbovine, Avian
IsotypeIgG1
FormatPE-ATTO 594 conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsWestern Blot (WB), ELISA (EIA), binds Protein-G, Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionBackground Info: Detects proteins containing acetylated lysine residues in ELISA and WBs. Does not detect non-acetylated lysine residues. Scientific Background: Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine Nepsilon development (5).
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS800100
Price$445
Order / More InfoAcetylated Lysine Antibody from MYBIOSOURCE INC.
Product Specific References1. Yang XJ. (2005). Oncogene. 24:1653-1662. 2. Hassig, C.A. and Schreiber, S.L. (1997). Curr. Opin. Chem. Biol. 1(3): 300-308. 3. Yang XJ. (2004). Bioessays 26:1076-1087. 4. Hughes, R.E. (2002). Curr. Biol. 12: R141-R143. 5. Vigushin, D.M. and Coombes, R.C. (2004). Curr. Cancer Drug Targets 4: 205-218.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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