GPR30 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGPR30
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: GPR30 antibody detects endogenous levels of total GPR30. Description: Receptor for estrogen.Function: G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotect
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane. Endoplasmic Reticulum Membrane. Golgi Apparatus Membrane. Protein has been detected in the cell membrane, endoplasmic reticulum and golgi apparatus. It is currently unclear whether this is a cell surface or intracellular receptor. Tissue Specificity: Expressed in placenta, endothelial and epithelial cells, non laboring and laboring term myometrium, fibroblasts and cancer-associated fibroblasts (CAF), prostate cancer cells and
Other Names[CEPR; Chemoattractant receptor-like 2; Chemokine receptor-like 2; CMKRL2; Constitutively expressed peptide like receptor; DRY12; FEG 1; FEG-1; Flow-induced endothelial G protein-coupled receptor; Flow-induced endothelial G-protein coupled receptor 1; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; G-protein coupled receptor 30; GPCR-BR; Gper; GPER_HUMAN; GPER1; GPR30; IL8-related receptor DRY12; Lergu; LERGU2; leucine rich protein in GPR30 3'UTR; LYGPR; Lymphocyte-derived G-protein coupled receptor; Membrane estrogen receptor; mER; MGC99678]
Gene, Accession #[GPR30], Gene ID: 2852, NCBI: NP_001035055.1, UniProt: Q99527
Catalog #MBS9604251
Price$240, $280
Order / More InfoGPR30 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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