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Antigenic Specificity | GPR30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GPR30 antibody detects endogenous levels of total GPR30. Description: Receptor for estrogen.Function: G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotect |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Endoplasmic Reticulum Membrane. Golgi Apparatus Membrane. Protein has been detected in the cell membrane, endoplasmic reticulum and golgi apparatus. It is currently unclear whether this is a cell surface or intracellular receptor. Tissue Specificity: Expressed in placenta, endothelial and epithelial cells, non laboring and laboring term myometrium, fibroblasts and cancer-associated fibroblasts (CAF), prostate cancer cells and |
Other Names | [CEPR; Chemoattractant receptor-like 2; Chemokine receptor-like 2; CMKRL2; Constitutively expressed peptide like receptor; DRY12; FEG 1; FEG-1; Flow-induced endothelial G protein-coupled receptor; Flow-induced endothelial G-protein coupled receptor 1; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; G-protein coupled receptor 30; GPCR-BR; Gper; GPER_HUMAN; GPER1; GPR30; IL8-related receptor DRY12; Lergu; LERGU2; leucine rich protein in GPR30 3'UTR; LYGPR; Lymphocyte-derived G-protein coupled receptor; Membrane estrogen receptor; mER; MGC99678] |
Gene, Accession # | [GPR30], Gene ID: 2852, NCBI: NP_001035055.1, UniProt: Q99527 |
Catalog # | MBS9604251 |
Price | $240, $280 |
Order / More Info | GPR30 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |