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Antigenic Specificity | Human CD161 |
Clone | [HP-3G10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | fluorescein (FITC) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161. |
Immunogen | n/a |
Other Names | [CLEC5B; NKRP1A; NKR-P1A; HNKR-P1a; KLRB1] |
Gene, Accession # | [CD161], Gene ID: 3820, NCBI: NP_002249.1, UniProt: Q12918 |
Catalog # | MBS2559128 |
Price | $100, $125, $165 |
Order / More Info | Human CD161 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |