DACH1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DACH1 |
| Clone | [740] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DACH1, a homologue of the Drosophila dachshund gene, is a key regulator of cell fate determination during eye, leg, and brain development in the fly. Through interacting with NCoR and Smad4, DACH1 is able to inhibit the transforming growth factor-beta (TGF-beta) signaling pathway. DACH1 can inhibit breast cancer cellular proliferation via cyclin D1, suggesting a possible role in tumor suppression. Additionally, DACH1 plays an important role in negative regulation of RANKL (Receptor activator of NF-kappaB ligand) gene expression in marrow stromal/preosteoblast cells, and loss of DACH1 expression might be involved in endometrial cancer progression. Four isoforms of DACH1 are produced by alternative splicing, but isoform1(97-110kd) is the pred |
| Immunogen | Immunogen: Fusion protein of DACH1 |
| Other Names | [DACH; Dach1; DACH1; Dachshund family transcription factor 1; dachshund homolog 1 (Drosophila); Dachshund homolog 1; Dachsund homolog 1; FLJ10138; OTTHUMP00000018494] |
| Gene, Accession # | [DACH1], Gene ID: 1602, NCBI: NP_004383.4, UniProt: Q9UI36 |
| Catalog # | MBS2542275 |
| Price | $220, $290, $435 |
| Order / More Info | DACH1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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