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Antigenic Specificity | ASC/TMS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ASC [apoptosis-associated speck-like protein containing a CARD (caspase-recruitment domain)] is a bimodel protein containing a pyrin/paad domain (PYD/PAAD) and a caspase recruitment domain (CARD) ASC is also known as TMS1 (target of methylation-induced silencing). In general proteins, like ASC/TMS1, containing PYD/PAAD and CARD domains play key roles in regulating apoptosis and inflammation signaling pathways. Mutations in a number of PYD/PAAD- and CARD-containing proteins have been linked to inflammatory diseases and cancer. There is evidence that ASC/TMS1 has roles in both apoptosis and inflammation signaling pathways.With respect to inflammation, ASC/TMS1 interacts with the CARD of procaspase-1 and induces aggregation of a protein comple |
Immunogen | Immunogen Information: A synthetic peptide of ASC/TMS1 protein (amino acids 83-102 GQLQAATHQGSGAAPAGIQA) was used as the immunogen for this antibody |
Other Names | [PYCARD; ASC; CARD5; TMS1; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; to ASC/TMS1; ASC/TMS1; ASC/TMS1], [PYCARD; PYCARD; ASC; TMS; TMS1; CARD5; TMS-1; ASC; CARD5; TMS1; hASC] |
Gene, Accession # | [ASC/TMS1], Gene ID: 29108, NCBI: Q9ULZ3.2, UniProt: Q9ULZ3 |
Catalog # | MBS668514 |
Price | $270 |
Order / More Info | ASC/TMS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |