ASC/TMS1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityASC/TMS1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatserum
Size0.05 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionASC [apoptosis-associated speck-like protein containing a CARD (caspase-recruitment domain)] is a bimodel protein containing a pyrin/paad domain (PYD/PAAD) and a caspase recruitment domain (CARD) ASC is also known as TMS1 (target of methylation-induced silencing). In general proteins, like ASC/TMS1, containing PYD/PAAD and CARD domains play key roles in regulating apoptosis and inflammation signaling pathways. Mutations in a number of PYD/PAAD- and CARD-containing proteins have been linked to inflammatory diseases and cancer. There is evidence that ASC/TMS1 has roles in both apoptosis and inflammation signaling pathways.With respect to inflammation, ASC/TMS1 interacts with the CARD of procaspase-1 and induces aggregation of a protein comple
ImmunogenImmunogen Information: A synthetic peptide of ASC/TMS1 protein (amino acids 83-102 GQLQAATHQGSGAAPAGIQA) was used as the immunogen for this antibody
Other Names[PYCARD; ASC; CARD5; TMS1; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; to ASC/TMS1; ASC/TMS1; ASC/TMS1], [PYCARD; PYCARD; ASC; TMS; TMS1; CARD5; TMS-1; ASC; CARD5; TMS1; hASC]
Gene, Accession #[ASC/TMS1], Gene ID: 29108, NCBI: Q9ULZ3.2, UniProt: Q9ULZ3
Catalog #MBS668514
Price$270
Order / More InfoASC/TMS1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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