Edit |   |
---|---|
Antigenic Specificity | ABL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN (microtubule-binding proteins). Phosphorylation of WASF3 is critical for the stimulation of lamellipodia formation and cell migration. Involved in the regulation of cell adhesion and motility through phospho |
Immunogen | Immunogen: A synthetic peptide of human ABL1 |
Other Names | [ABL; JTK7; p150; c-ABL; v-abl; CHDSKM; c-ABL1; bcr/abl] |
Gene, Accession # | [ABL1], Gene ID: 25, NCBI: NP_005148.2, UniProt: P00519 |
Catalog # | MBS8544001 |
Price | $280 |
Order / More Info | ABL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |