Phospho-PAK1/2/3 (S144+S141+S139) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Phospho-PAK1/2/3 (S144+S141+S139) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Phospho-PAK1/2/3 (S144+S141+S139) |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilamen |
| Immunogen | Immunogen: A synthesized peptide derived from human Phospho-PAK1/2/3 (S144 S141 S139) Subcellular Localization: Cytoplasm. Tissue Specificity: Restricted to the nervous system. Highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. |
| Other Names | [Serine/threonine-protein kinase PAK 3; 2.7.11.1; Beta-PAK; Oligophrenin-3; p21-activated kinase 3; PAK-3; PAK3; OPHN3] |
| Gene, Accession # | [PAK1/2/3], Gene ID: 5063, NCBI: NP_001121638.1, UniProt: O75914 |
| Catalog # | MBS1750277 |
| Price | $160, $340, $340 |
| Order / More Info | Phospho-PAK1/2/3 (S144+S141+S139) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies