Edit |   |
---|---|
Antigenic Specificity | Disabled (NT) |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | mouse |
Isotype | n/a |
Format | ammonium sulfate precipitate |
Size | 0.25 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Disruption of the disabled-1 gene (Dab1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. Disabled ?1 acts downstream of reelin in a signalling pathway. |
Immunogen | Immunogen: Recombinant protein corresponding to amino acids 1-179 of mouse disabled coupled to a GST fusion protein. |
Other Names | [Disabled homolog 1; DAB1], [Dab1; Dab1; scm; scr; yot; AI956902; scrambler; C630028C02Rik] |
Gene, Accession # | Gene ID: 13131, NCBI: NP_034144.1, UniProt: P97318 |
Catalog # | MBS395918 |
Price | $340 |
Order / More Info | Disabled (NT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |