Disabled (NT) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDisabled (NT)
Clonepolyclonal
Host SpeciesSheep
Reactive Speciesmouse
Isotypen/a
Formatammonium sulfate precipitate
Size0.25 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDisruption of the disabled-1 gene (Dab1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. Disabled ?1 acts downstream of reelin in a signalling pathway.
ImmunogenImmunogen: Recombinant protein corresponding to amino acids 1-179 of mouse disabled coupled to a GST fusion protein.
Other Names[Disabled homolog 1; DAB1], [Dab1; Dab1; scm; scr; yot; AI956902; scrambler; C630028C02Rik]
Gene, Accession #Gene ID: 13131, NCBI: NP_034144.1, UniProt: P97318
Catalog #MBS395918
Price$340
Order / More InfoDisabled (NT) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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