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Antigenic Specificity | CK16 |
Clone | [6F6] |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The CK16 Mouse Monoclonal antibody detects endogenous CK16 proteins. (~51KD). Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining doe |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CK16] |
Catalog # | MBS8501586 |
Price | $300 |
Order / More Info | CK16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |