TBC1D1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTBC1D1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionTBC1D1 Antibody: TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity.
ImmunogenImmunogen: TBC1D1 antibody was raised against a 22 amino acid synthetic peptide from near the carboxy terminus of human TBC1D1. Buffer: TBC1D1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[TBC1D1; TBC; TBC1; KIAA1108; TBC1 domain family member 1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1], [TBC1D1; TBC1D1; TBC; TBC1; KIAA1108]
Gene, Accession #[TBC1D1], Gene ID: 23216, NCBI: NP_055988, UniProt: Q86TI0
Catalog #MBS151090
Price$375
Order / More InfoTBC1D1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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