ATF6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATF6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionATF6 Antibody: Disruptions of protein folding and maturation in the endoplasmic reticulum (ER) result in the activation of the unfolded protein response (UPR), an integrated cellular signaling pathway that transmits information from the ER lumen to the cytoplasm and nucleus. Activating transcription factor 6 (ATF6) as well as the ER-transmembrane protein kinases IRE1p and PERK are the major transducers of the UPR. ATF6 is an ER transmembrane protein that is normally bound to the ER chaperone GRP78, but upon ER stress is released from GRP78 and proteolytically cleaved to yield a cytosolic fragment which then migrates to the nucleus, and together with the transcription factor XBP-1, activates transcription of UPR-responsive genes. ATF6 has tw
ImmunogenImmunogen: ATF6 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human ATF6. Buffer: ATF6 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[ATF6; ATF6A; Cyclic AMP-dependent transcription factor ATF-6 alpha; Activating transcription factor 6 alpha; cAMP-dependent transcription factor ATF-6 alpha; activating transcription factor 6], [ATF6; ATF6; ATF6A; cAMP-dependent transcription factor ATF-6 alpha; ATF6-alpha]
Gene, Accession #[ATF6], Gene ID: 22926, NCBI: NP_031374, UniProt: P18850
Catalog #MBS150934
Price$375
Order / More InfoATF6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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