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Antigenic Specificity | ATF6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ATF6 Antibody: Disruptions of protein folding and maturation in the endoplasmic reticulum (ER) result in the activation of the unfolded protein response (UPR), an integrated cellular signaling pathway that transmits information from the ER lumen to the cytoplasm and nucleus. Activating transcription factor 6 (ATF6) as well as the ER-transmembrane protein kinases IRE1p and PERK are the major transducers of the UPR. ATF6 is an ER transmembrane protein that is normally bound to the ER chaperone GRP78, but upon ER stress is released from GRP78 and proteolytically cleaved to yield a cytosolic fragment which then migrates to the nucleus, and together with the transcription factor XBP-1, activates transcription of UPR-responsive genes. ATF6 has tw |
Immunogen | Immunogen: ATF6 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human ATF6. Buffer: ATF6 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ATF6; ATF6A; Cyclic AMP-dependent transcription factor ATF-6 alpha; Activating transcription factor 6 alpha; cAMP-dependent transcription factor ATF-6 alpha; activating transcription factor 6], [ATF6; ATF6; ATF6A; cAMP-dependent transcription factor ATF-6 alpha; ATF6-alpha] |
Gene, Accession # | [ATF6], Gene ID: 22926, NCBI: NP_031374, UniProt: P18850 |
Catalog # | MBS150934 |
Price | $375 |
Order / More Info | ATF6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |