Edit |   |
---|---|
Antigenic Specificity | Human Adiponectin |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for human Adiponectin denatured and native forms. Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affi |
Immunogen | Immunogen: Recombinant Human Adiponectin Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-136131 |
Other Names | [30 kDa adipocyte complement-related protein], [ADIPOQ; ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1; ACDC; ACRP30; APM1; GBP28; ACRP30; apM-1] |
Gene, Accession # | Gene ID: 9370, NCBI: NP_001171271.1, UniProt: Q15848 |
Catalog # | MBS1488163 |
Price | $185, $265 |
Order / More Info | Human Adiponectin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |