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Antigenic Specificity | Orf Virus VEGF-E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Orf virus |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | A DNA sequence encoding the mature variant of ov-VEGF-E isolate D1701 was expressed in E. coli as a 132 amino acid residue fusion protein with an N-terminal His-tag sequence and a thrombin cleavage site. Recombinant VEGF-E homodimer was dimerized in vitro and has a predicted mass of approximately 35 kDa. Based on sequence similarity to VEGF-A, a gene encoding a VEGF homologue has recently been discovered in the genome of Orf virus (OV). Different isolates of Orf virus show significant amino acid sequence similarity to VEGF-A and described as a viral virulence factor that appears to be derived from captured host genes. All eight Cysteine residues of the central Cysteine knot motif characteristic of members of the VEGF family are conserved am |
Immunogen | Immunogen: Recombinant ov-VEGF-E (RT #300-045). Preparation: Produced from sera of rabbits immunized with highly pure recombinant ov-VEGF-E produced in E. coli. |
Other Names | n/a |
Gene, Accession # | [VEGF-E], NCBI: AAD03735.1, UniProt: Q9YMF3 |
Catalog # | MBS691106 |
Price | $280 |
Order / More Info | Orf Virus VEGF-E Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Dehio et al., 1999 EMBO J. 18:363-374 2. Lyttle et al., 1994 J. Virol 68:84-92 3. Wise et al., 1999 Proc. Natl. Acad. Sci USA 96:3071-3076 |