Drosophila HSP70 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDrosophila HSP70
Clone[7FB]
Host SpeciesRat
Reactive SpeciesDrosophila
IsotypeIgG2B
FormatProtein G purified
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA (EIA)
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DescriptionHSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 5O% identity (2). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (3). When HSC70 (constitutively expressed) present in mammalian cells was truncated, ATP binding activity was found to reside in an
ImmunogenImmunogen: Prepared from Drosophila tissue culture cells heat shocked at 36.5 degree C for 3 hours, and isolated using SDS PAGE. Immunogen Species: Drosophila
Other Names[HSP70Bb; Heat Shock Protein 70Bb; dHSP70; HSP70b; HSP70B; Dm-HSP70; HSP70 : FITC; Rat Drosophila HSP70, Clone 7FB; Hsp70; Hsp70], [Hsp70Bb; Hsp70Bb; Bb; CG31359; dhsp70; dHsp70; Dm-hsp70; DmelCG31359; DMHSP7D1; Hsp 70; hsp-70; Hsp-70; hsp70; Hsp70; HSP70; hsp70 87C; Hsp70(87C); Hsp70A7d; hsp70B; Hsp70B; hsp70Bb; Hsp70Bbc; Hsp70Bc; Heat shock protein 70Bb]
Gene, Accession #[HSP70], Gene ID: 48582, NCBI: NP_524927.2, UniProt: Q9BIS2
Catalog #MBS806974
Price$415
Order / More InfoDrosophila HSP70 Antibody from MYBIOSOURCE INC.
Product Specific References1. Welch W.J. and Suhan J.P. (1986) J Cell Biol. 103: 2035-2050. 2. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J.Mol. Evol. 38(1): 1-17. 3. Rothman J. (1989) Cell 59: 591-601. 4. DeLuca-Flaherty et al. (1990) Cell 62: 875-887. 5. Bork P., Sander C. & Valencia A. (1992) Proc. Nut1 Acad. Sci. USA 89: 7290-7294.6. Fink A.L. (1999) Physiol. Rev. 79: 425-449. 7. Galan A., et al. (2000) J. Biol. Chem. 275: 11418-11424. 8. Kondo T., et al. (2000) J. Biol. Chem. 275: 8872-8879.9. Misaki T., et al. (1994) Clin. Exp. Immun. 98: 234-239. 10. Pockley A.G., et al. (1998) Immunol. Invest. 27: 367-377. 11. Moon I.S., et al. (2001) Cereb Cortex 11(3): 238-248. 12. Dressel et al. (2000) J. Immunol. 164: 2362-2371. 13. Verma A.K., et al. (2007) Fish and Shellfish Immunology. 22(5): 547-555. 14. Banduseela V.C., et al. (2009) Physiol Genomics. 39(3): 141-159.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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