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Antigenic Specificity | KIDINS220 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow; dog; guinea pig; horse; human; mouse; rat; zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | kinase D-interacting substrate, 220kDaTarget Description: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development an |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIDINS220 |
Other Names | [Kinase D-interacting substrate of 220 kDa; Kinase D-interacting substrate of 220 kDa; kinase D-interacting substrate of 220 kDa; kinase D interacting substrate 220; Ankyrin repeat-rich membrane-spanning protein] |
Gene, Accession # | [KIDINS220], Gene ID: 57498, NCBI: Q9ULH0.3, UniProt: Q9ULH0 |
Catalog # | MBS3209512 |
Price | $335 |
Order / More Info | KIDINS220 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |