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Antigenic Specificity | Human ULBP2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein which belongs to the MHC class I family. ULBP2/N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2/N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. |
Immunogen | Immunogen: Recombinant Human ULBP2 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [ULBP2; NKG2D ligand 2; NKG2D ligand 2; UL16 binding protein 2; ALCAN-alpha; Retinoic acid early transcript 1H; UL16-binding protein 2] |
Gene, Accession # | [ULBP2 ], Gene ID: 80328 |
Catalog # | MBS2544341 |
Price | $215, $330, $500 |
Order / More Info | Human ULBP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |