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Antigenic Specificity | RAB23 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by |
Immunogen | Immunogen: Recombinant human Ras-related protein Rab-23 protein (1-237AA) |
Other Names | [Ras-related protein Rab-23; RAB23; HSPC137] |
Gene, Accession # | [RAB23], Gene ID: 51715, NCBI: NP_001265595.1, UniProt: Q9ULC3 |
Catalog # | MBS7043729 |
Price | $120, $160 |
Order / More Info | RAB23 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |