CHRM2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CHRM2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CHRM2 antibody detects endogenous levels of total CHRM2. Function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.Subunit Structure: Interacts with ARRB1 and ARRB2. Interacts with RACK1; the interaction regulates CHRM2 internalization.Post-translational Modifications: Phosphorylated in response to agonist treatment.Similarity: Belong |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Cell Junction > Synapse > Postsynaptic Cell Membrane. Tissue Specificity: Up-regulated in response to enterovirus 71 (EV71) infection. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (91%), Sheep (100%), Rabbit (100%), Dog (91%), Chicken (91%), Xenopus (91%) |
| Other Names | [7TM receptor; Acetylcholine receptor, muscarinic, 2; AChR; Acm2; ACM2_HUMAN; Cholinergic receptor muscarinic 2; Cholinergic receptor, muscarinic 2, cardiac; Cholinergic receptor, muscarinic 2, isoform a; Cholinergic receptor, muscarinic 2a; CHRM 2; CHRM2; chrm2a; CM2; FLJ43243; HM 2; HM2; M2; M2 muscarinic receptor; M2-mAChR; MGC120006; MGC120007; Muscarinic acetylcholine receptor M2; Muscarinic M2 receptor] |
| Gene, Accession # | [CHRM2], Gene ID: 1129, NCBI: NP_000730.1, UniProt: P08172 |
| Catalog # | MBS9606360 |
| Price | $240, $280 |
| Order / More Info | CHRM2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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