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Antigenic Specificity | MME (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MME antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-132 amino acids from the N-terminal region of human MME. Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers. |
Immunogen | n/a |
Other Names | [Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 2411; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10; MME; EPN] |
Gene, Accession # | [MME], Gene ID: 4311, NCBI: NP_000893.2, UniProt: P08473 |
Catalog # | MBS9207337 |
Price | $165, $370 |
Order / More Info | MME (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Letarte M.,et al.J. Exp. Med. 168:1247-1253(1988). Shipp M.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:4819-4823(1988). D'Adamio L.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:7103-7107(1989). Ota T.,et al.Nat. Genet. 36:40-45(2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |