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Antigenic Specificity | STAM2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). |
Immunogen | Immunogen: Recombinant human Signal transducing adapter molecule 2 protein (C-150AA) |
Other Names | [Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein; STAM2; HBP] |
Gene, Accession # | [STAM2], Gene ID: 10254, NCBI: NP_005834.4, UniProt: O75886 |
Catalog # | MBS7044275 |
Price | $120, $160 |
Order / More Info | STAM2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |