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Antigenic Specificity | MAP3K7 |
Clone | [4E7E10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Immunogen | Immunogen: Purified recombinant fragment of human MAP3K7 (AA: 471-579) expressed in E. Coli. |
Other Names | [TAK1; MEKK7; TGF1a] |
Gene, Accession # | [MAP3K7], Gene ID: 6885, NCBI: NP_003179.1, UniProt: O43318 |
Catalog # | MBS8539471 |
Price | $280 |
Order / More Info | MAP3K7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |