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Antigenic Specificity | KDM7A/JHDM1D (aa290-316) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mL |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This JHDM1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-316 amino acids from the Central region of human JHDM1D. Histone demethylase required for brain development. Specificallydemethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20'residue (H4K20Me1), thereby playing a central role in histone code.Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, ithas no demethylase activity toward H3K9me2, while it has high activitytoward H3K27me2. |
Immunogen | n/a |
Other Names | [Rabbit to Human KDM7A/JHDM1D; KDM7A; KIAA1718; Lysine-specific demethylase 7; JHDM1D; KDM7] |
Gene, Accession # | [KDM7A/JHDM1D], Gene ID: 80853, NCBI: NP_085150.1, UniProt: Q6ZMT4 |
Catalog # | MBS2401805 |
Price | $530 |
Order / More Info | KDM7A/JHDM1D (aa290-316) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |