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Antigenic Specificity | Ubinuclein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Ubinuclein antibody detects endogenous levels of total Ubinuclein. Function: Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly.Subunit Structure: Component of a complex that includes at least ASF1A, CABIN1, HIRA, histone H3.3 and UBN1. Interacts with Epstein-Barr virus BZLF1. Interacts with HIRA (via WD repeat domain); the interaction is direct. Interacts with ASF1A, CEBPA, TJP1, TJP2 and TJP3.Similarity: Belongs to the ubinuclein family. |
Immunogen | Immunogen: A synthesized peptide derived from human Ubinuclein Subcellular Location: Nuclear Tissue Specificity: Ubiquitous. Also expressed in numerous tumors and cancer cell lines. |
Other Names | [Ubinuclein 1; Ubinuclein; Ubiquitously expressed nuclear protein; VT; VT4] |
Gene, Accession # | [UBN1], Gene ID: 29855, NCBI: NP_001072982.1, UniProt: Q9NPG3 |
Catalog # | MBS9609190 |
Price | $240, $280 |
Order / More Info | Ubinuclein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |