Ubinuclein Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUbinuclein
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Ubinuclein antibody detects endogenous levels of total Ubinuclein. Function: Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly.Subunit Structure: Component of a complex that includes at least ASF1A, CABIN1, HIRA, histone H3.3 and UBN1. Interacts with Epstein-Barr virus BZLF1. Interacts with HIRA (via WD repeat domain); the interaction is direct. Interacts with ASF1A, CEBPA, TJP1, TJP2 and TJP3.Similarity: Belongs to the ubinuclein family.
ImmunogenImmunogen: A synthesized peptide derived from human Ubinuclein Subcellular Location: Nuclear Tissue Specificity: Ubiquitous. Also expressed in numerous tumors and cancer cell lines.
Other Names[Ubinuclein 1; Ubinuclein; Ubiquitously expressed nuclear protein; VT; VT4]
Gene, Accession #[UBN1], Gene ID: 29855, NCBI: NP_001072982.1, UniProt: Q9NPG3
Catalog #MBS9609190
Price$240, $280
Order / More InfoUbinuclein Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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