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Antigenic Specificity | STEAP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: STEAP4 antibody detects endogenous levels of total STEAP4. Function: Metalloreductase that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+ (By similarity). Uses NADP+ as acceptor (By similarity). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance (PubMed:18430367, PubMed:18381574). Involved in inflammatory arthritis, through the regulation of inflammatory cytokines (PubMed:19660107). Inhibits anchorage-independent cell proliferation (PubMed:19787193).Subunit Structure: Homodimer (By similarity). Interacts with PTK2/FAK1; the interaction may regulate PTK2 phosphorylation.Similarity: Belongs to the ST |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Golgi Apparatus Membrane. Tissue Specificity: Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages. |
Other Names | [alpha-induced protein 9; Metalloreductase STEAP4; six transmembrane prostate protein 2; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP 2; STAMP2; STEA4_HUMAN; STEAP 4; STEAP family member 4; STEAP4; TIARP; TNFAIP 9; TNFAIP9; Tumor necrosis factor; tumor necrosis factor, alpha-induced protein 9; tumor necrosis-alpha-induced adipose-related protein] |
Gene, Accession # | [STEAP4], Gene ID: 79689, NCBI: NP_001192244.1, UniProt: Q687X5 |
Catalog # | MBS9604783 |
Price | $240, $280 |
Order / More Info | STEAP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |