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Antigenic Specificity | ABL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The c-Abl proto-oncogene encodes a nonreceptor protein tyrosine kinase that is ubiquitously expressed and highly conserved in metazoan evolution. c-Abl protein is distributed in both the nucleus and the cytoplasm of cells. It is implicated in regulating cell proliferation, differentiation, apoptosis, cell adhesion and stress responses (1-3). c-Abl kinase activity is increased in vivo by diverse physiological stimuli including integrin activation, PDGF stimulation and binding to c-Jun, Nck and RFX1 (2, 4). The in vivo mechanism of regulation of c-Abl kinase activity is not completely understood. Tyr245 is located in the linker region between the SH2 and catalytic domains. This positioning is conserved among Abl family members. Phosphorylatio |
Immunogen | Immunogen: C term -peptide of human ABL1 Observed Molecular Weight: 123kDa |
Other Names | [ABL1; ABL; JTK7; bcr/abl; c-ABL; p150; v-abl] |
Gene, Accession # | [ABL1], Gene ID: 25, NCBI: AAA88012.1 |
Catalog # | MBS2520419 |
Price | $150, $225, $360 |
Order / More Info | ABL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |