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Antigenic Specificity | DR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | DEAE purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DR4 antibody has no cross reaction to DR5. DR4 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TN |
Immunogen | Immunogen: DR4 antibody was raised against a 20 amino acid peptide near the amino terminus of human DR4. Buffer: DR4 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [DR4; DR4; APO2; CD261; TRAILR1; TRAILR-1; DR4; Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TRAIL receptor 1; tumor necrosis factor receptor superfamily, member 10a], [TNFRSF10A; TNFRSF10A; DR4; APO2; CD261; TRAILR1; TRAILR-1; APO2; DR4; TRAILR1; TRAIL receptor 1; TRAIL-R1] |
Gene, Accession # | [TNFRSF10A], Gene ID: 8797, NCBI: AAC51226, UniProt: O00220 |
Catalog # | MBS151351 |
Price | $375 |
Order / More Info | DR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |