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Antigenic Specificity | K22E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: K22E antibody detects endogenous levels of total K22E. Function: Probably contributes to terminal cornification (PubMed:1380918). Associated with keratinocyte activation, proliferation and keratinization (PubMed:12598329). Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity).Subunit Structure: Heterotetramer of two type I and two type II keratins. Associates with KRT10 (By similarity).Similarity: Belongs to the intermediate filament family. |
Immunogen | Immunogen: A synthesized peptide derived from human K22E Subcellular Location: Cytoplasmic Tissue Specificity: Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however exp |
Other Names | [CK 2e; Cytokeratin-2e; Epithelial keratin-2e; K2e; Keratin type II cytoskeletal 2 epidermal; Keratin-2 epidermis; KRT2; KRT2A; KRT2E; Type-II keratin Kb2] |
Gene, Accession # | [K22E], Gene ID: 3849, NCBI: NP_000414.2, UniProt: P35908 |
Catalog # | MBS9609325 |
Price | $240, $280 |
Order / More Info | K22E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |