Edit |   |
---|---|
Antigenic Specificity | BCL10 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle terminal region of human BCL10 |
Other Names | [B-cell lymphoma/leukemia 10 isoform 1; B-cell lymphoma/leukemia 10; B-cell lymphoma/leukemia 10; BCL10 immune signaling adaptor; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10] |
Gene, Accession # | [BCL10], Gene ID: 8915, NCBI: NP_003912.1, UniProt: O95999 |
Catalog # | MBS3223366 |
Price | $335 |
Order / More Info | BCL10 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |